Personalised Dermatology
Personalised medicine in dermatology tailors diagnosis, treatment, and prevention to individual patient characteristics.
This JEADV Collection highlights advances in multi-omics, biomarkers, AI, risk stratification, and targeted therapeutics. Emphasising shared decision-making and equitable care, it showcases the shift from phenotype-based management to data-driven, individualised dermatology, where treatments are guided by molecular signatures, clinical endotypes, and patient priorities.
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Results:
Exposome Environment & Systems Medicine
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Inflammatory Niches as Spatial Drivers of Disease Mechanisms and Targets for Personalized TreatmentRundong Jiang, Zhiqin Fang, Lam C. Tsoi, Johann E. Gudjonsson
Review Article November 2025 -
The Exposomal Imprint on Rosacea: More than Skin DeepKaterina Grafanaki, Daniella Bakoli Sgourou, Alexandros Maniatis, Efstathia Pasmatzi
Review Article October 2025 -
Cardiovascular-kidney-metabolic health, genetic predisposition and incident risk of psoriasis Gang Zheng, Yixiao Zhang, Han Su, Honghao Yang, Zheng Ma, Liuxin Li, Yuqian Li, Chao Ji, Yang Xia, Yuhong Zhao
Original Article July 2025
Foundational & Conceptual Frameworks
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Why We Choose to Publish on Personalised Medicine in DermatologyJo Lambert, Curdin Conrad
Editorial February 2026 -
The Renaissance of Therapeutic Options in DermatologyMegan Lau, Joseph Largen, Ester Del Duca, Helen He, Emma Guttman-Yassky
Editorial February 2026 -
Personalized medicine: The future, or wishful thinking?C. Posch
Editorial February 2026 -
Dermatology 2.0: Precision medicine for inflammatory skin diseasesJeremy Di Domizio, Antoine Girardin, Curdin Conrad, Teofila Seremet, Michel Gilliet
Review Article December 2025 -
Precision Dermatology 2050: AI-Driven Personalized Monitoring, and Individualized TreatmentFelicitas Schierle, Jon Lindström Bolmgren, Mette Deleuran, Oliver Welter, Vanessa Gebauer
Review Article December 2025
Multi-Omics Molecular Profiling & Biomarkers
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Multi-omics profiling of chronic immune-mediated skin diseases: SKINERGY protocol & strategic evaluationN. G. Koster, J. M. P. A. van den Reek, E. M. G. J. de Jong, S. van Beugen, A. I. M. van Laarhoven, I. Haeck, M. de Bruin-Weller, M. L. Schuttelaar, B. Horvath, A. Gostyński, A. Knulst, M. H. Vermeer, L. Nguyen, L. Gerbens, P. Spuls, M. A. Middelkamp-Hup, V. Exadaktylos, T. Niemeyer-van der Kolk, A. R. Schrader, A. M. Sluijmers, J. Versteeg, B. W. M. Arents, I. van Ee, J. L. A. G. van der Zon, M. de Leeuw, T. de Leeuw, P. van den Broek, C. Berkhof, D. Vellinga, S. Weidinger, S. Dubrac, Y. Li, M. van Steensel, M. Marchetti-Deschmann, M. Maurer, H. van der Zee, J. Damman, D. J. Hijnen, F. Wijk, M. M. B. Seyger, H. Röckmann, D. M. W. Balak, M. B. A. van Doorn, R. Rissmann, The Next Generation ImmunoDermatology (NGID) consortium
Original Article February 2026 -
High-throughput proteomics uncovers molecular clusters and biomarkers of severity in bullous pemphigoidLaura Calabrese, Giulia Vallini, Lorenzo Bonacchi, Alessandra Cartocci, Martina D'Onghia, Maria Efenesia Baffa, Jole Serra, Caterina Giorgia Focacci, Carlo Pipitò, Azzurra Sirchio, Alessandro Pucci, Giuseppe Rubens Pascucci, Donato Amodio, Francesco De Logu, Romina Nassini, Lucrezia Timotei, Pietro Rubegni, Emiliano Antiga, Roberto Maglie
Original Article December 2025 -
Inflammatory Niches as Spatial Drivers of Disease Mechanisms and Targets for Personalized TreatmentRundong Jiang, Zhiqin Fang, Lam C. Tsoi, Johann E. Gudjonsson
Review Article November 2025 -
Machine learning-derived serum protein signatures as biomarkers for checkpoint inhibition in melanomaKatrin Schaper-Gerhardt, Nina Flatt, Uzair Rana, Antje Walter, Booje Oostermann, Yenny Angela, Viola K. DeTemple, Corinna Kochanek, Jan Borggrefe, Imke von Wasielewski, Ralf Gutzmer
Letter to the Editor November 2025 -
From Tissue to Target: Molecular Diagnostics in Difficult-to-Diagnose Psoriasis and EczemaJorien Papeleu, Sofie De Schepper, Jo Lambert
Letter to the Editor October 2025 -
The expression of pruritus-associated genes in seven skin diseases: Evidence from microarrayManahel Mahmood Alsabbagh
Original Article October 2025 -
The evolving genetic landscape of ILVEN: A comprehensive reviewMarra Aghajani, Jessie Tong Lu, John W. Frew, Deshan F. Sebaratnam
Review Article October 2025 -
T helper and IL-20 cytokine signatures distinguish atopic dermatitis from contact dermatitis subtypesAxel De Greef, Léna Puigdevall, Laurence de Montjoye, Anne Herman, Emilie Hendrickx, Laure Dumoutier, Marie Baeck
Letter to the Editor September 2025 -
Increased activation of ErbB and NFκB signalling pathways in Darier disease affected skinNancy Ernst, Ralf J. Ludwig, Artem Vorobyev
Letter to the Editor July 2025 -
Type I interferon and type I interferon induced biomarkers in dermatomyositis: A systematic reviewRyan S. Q. Geng, Samiha Mohsen, Kaitlyn Ramsay, Edgar Akuffo-Addo, Richie Jeremian, Ernest Choy, Vincent Piguet
Letter to the Editor June 2025 -
Skin's molecular signature may help guide treatment of complex inflammatory skin diseasesValérie Beaulieu, Amandine Mosnier, Hugo Rimet, Anne-Camille Garreau, Coline Jaulent-Darmaisin, Louise Jaulent, Rima Fathallah, Frédéric Bérard, Florence Hacard, Jean-François Nicolas, Marc Vocanson, Audrey Nosbaum, Marine-Alexia Lefevre, Marie Tauber
Letter to the Editor May 2025
Oncology & Precision Cancer Care
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Personalized Care for Older Skin Cancer Patients: Impact of Frailty Screening on Treatment DecisionsEsther Groll, Zsanna Hetényi, Ella Kokkola, Lisanne Holman, Suzanne Festen, Emoke Rácz
Letter to the Editor January 2026 -
Machine learning-derived serum protein signatures as biomarkers for checkpoint inhibition in melanomaKatrin Schaper-Gerhardt, Nina Flatt, Uzair Rana, Antje Walter, Booje Oostermann, Yenny Angela, Viola K. DeTemple, Corinna Kochanek, Jan Borggrefe, Imke von Wasielewski, Ralf Gutzmer
Letter to the Editor November 2025 -
Precision medicine in cutaneous melanoma - a comprehensive reviewMarkus Reitmajer, Lukas Flatz
Review Article October 2025 -
Modest psoriasis risk from cardiometabolic progression: Genetics, patterns and limitations in a Biobank studyShiuan-Chih Chen, Chin-Feng Tsai
Letter to the Editor September 2025 -
Cardiovascular-kidney-metabolic health, genetic predisposition and incident risk of psoriasis Gang Zheng, Yixiao Zhang, Han Su, Honghao Yang, Zheng Ma, Liuxin Li, Yuqian Li, Chao Ji, Yang Xia, Yuhong Zhao
Original Article July 2025
Patient-Centred Personalisation & Shared Decision-Making
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Building the foundations for an international patient-centred outcome set for psoriasis: a scoping studyEmma Vyvey, Rani Soenen, Hazel H. Oon, Sicily Mburu, Maren Awici-Rasmussen, Azura Mohd Affandi, Wayne Gulliver, Siew Eng Choon, Tiago Torres, Allison FitzGerald, Alvaro Gonzalez-Cantero, Anna López-Ferrer, Chih-Hung Lee, Fernando Valenzuela, Julia-Tatjana Maul, Luis Puig, Masanori Okuse, Mohamed EL-Komy, Peter Foley, Ron Vender, Wolf-Henning Boehncke, Josef Pohunek, Ya Hsin Wang, Angela Londoño-García, Gail Todd, Margarita Velasquez-Lopera, Mark Lebwohl, Edmund Lau, Marcus Schmitt-Egenolf, Niels Hilhorst, Spencer Connell, Elfie Deprez, Nanja van Geel, Christopher Griffiths, Peter Van de Kerkhof, Jo Lambert
Original Article February 2026 -
Advancing dermatologic patient decision aids: the need for standardised reporting and development practices Ciara Drumm, Blaithin Moriarty, Aoife Lally
Letter to the Editor February 2026 -
Personalising treatment for multiple actinic keratoses with the validation of a patient decision aid Ciara Drumm, Aoife Moloney, Louise Fleming, Imelda Morgan, Ciara Keating, Aisling Ryan, Roisin Dolan, Blaithin Moriarty, Aoife Lally
Letter to the Editor January 2026 -
Personalized Care for Older Skin Cancer Patients: Impact of Frailty Screening on Treatment DecisionsEsther Groll, Zsanna Hetényi, Ella Kokkola, Lisanne Holman, Suzanne Festen, Emoke Rácz
Letter to the Editor January 2026 -
Novel Treatment Approaches for Keloids and Hypertrophic Scars in Skin of ColorAndy D. Lee, Sean Jeong, Rachel Kim, Kristen A. R. Yee, Megan Park, Ryan S. Q. Geng, Cathryn Sibbald, Robert Bobotsis
Letter to the Editor December 2025 -
Personalised medicine in vitiligo: a guide for daily practiceReinhart Speeckaert, Julien Seneschal, Albert Wolkerstorfer, Nanja van Geel
Review Article October 2025
Predictive Modelling AI & Digital Dermatology
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Precision Dermatology 2050: AI-Driven Personalized Monitoring, and Individualized TreatmentFelicitas Schierle, Jon Lindström Bolmgren, Mette Deleuran, Oliver Welter, Vanessa Gebauer
Review Article December 2025 -
Machine learning-derived serum protein signatures as biomarkers for checkpoint inhibition in melanomaKatrin Schaper-Gerhardt, Nina Flatt, Uzair Rana, Antje Walter, Booje Oostermann, Yenny Angela, Viola K. DeTemple, Corinna Kochanek, Jan Borggrefe, Imke von Wasielewski, Ralf Gutzmer
Letter to the Editor November 2025 -
Automating Skin Colour Assessment Using 3D Total-Body Photography: A Proof-of-Concept StudyChantal Rutjes, Clare A. Primiero, Adam Mothershaw, Brigid Betz-Stablein, Nicholas M. Muller, Timothy J. Liu, Aideen McInerney-Leo, Monika Janda, Hans Peter Soyer, Dilki Jayasinghe
Letter to the Editor October 2025 -
Personalised Dermatologic Communication with Large Language Models on High-Stakes PersonasAhmet Ugur Atilan, Niyazi Cetin
Letter to the Editor October 2025 -
Risk stratification in anti-MDA5+ dermatomyositis-related interstitial lung disease by using cluster analysisWenzhang He, Beibei Cui, Zhigang Chu, Xuan Huang, Jing Liu, Xue Li, Yinqiu Wang, Xueting Pang, Hui Lin, Liqing Peng
Original Article July 2025 -
Ultra-high frequency ultrasound predicts baricitinib response in alopecia areata: Towards personalized treatmentFlavia Manzo Margiotta, Alessandra Michelucci, Bianca Cei, Giorgia Salvia, Giammarco Granieri, Alessandra Biagi, Riccardo Morganti, Marco Romanelli, Valentina Dini
Letter to the Editor October 2025
Risk Stratification & Predictive Medicine
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Building the foundations for an international patient-centred outcome set for psoriasis: a scoping studyEmma Vyvey, Rani Soenen, Hazel H. Oon, Sicily Mburu, Maren Awici-Rasmussen, Azura Mohd Affandi, Wayne Gulliver, Siew Eng Choon, Tiago Torres, Allison FitzGerald, Alvaro Gonzalez-Cantero, Anna López-Ferrer, Chih-Hung Lee, Fernando Valenzuela, Julia-Tatjana Maul, Luis Puig, Masanori Okuse, Mohamed EL-Komy, Peter Foley, Ron Vender, Wolf-Henning Boehncke, Josef Pohunek, Ya Hsin Wang, Angela Londoño-García, Gail Todd, Margarita Velasquez-Lopera, Mark Lebwohl, Edmund Lau, Marcus Schmitt-Egenolf, Niels Hilhorst, Spencer Connell, Elfie Deprez, Nanja van Geel, Christopher Griffiths, Peter Van de Kerkhof, Jo Lambert
Original Article February 2026 -
Modest psoriasis risk from cardiometabolic progression: Genetics, patterns and limitations in a Biobank studyShiuan-Chih Chen, Chin-Feng Tsai
Letter to the Editor September 2025 -
Cardiovascular-kidney-metabolic health, genetic predisposition and incident risk of psoriasis Gang Zheng, Yixiao Zhang, Han Su, Honghao Yang, Zheng Ma, Liuxin Li, Yuqian Li, Chao Ji, Yang Xia, Yuhong Zhao
Original Article July 2025 -
Risk stratification in anti-MDA5+ dermatomyositis-related interstitial lung disease by using cluster analysisWenzhang He, Beibei Cui, Zhigang Chu, Xuan Huang, Jing Liu, Xue Li, Yinqiu Wang, Xueting Pang, Hui Lin, Liqing Peng
Original Article July 2025
Stratified & Targeted Therapeutics
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CAR T-cell therapy in autoimmune skin diseaseAntonia Schett, Georg Schett
Editorial February 2026 -
Therapeutic Advances in Pruritus as a Model of Personalized MedicineKelsey Auyeung, Ramsey Kubofcik, Brian S. Kim
Review Article November 2025 -
Hair follicle stem cell fate supports distinct clinical endotypes in Hidradenitis SuppurativaAudrey Onfroy, Francette Jean-Louis, Philippe Le Corvoisier, Fanny Coulpier, Kévin Muret, Eric Bonnet, Raphaele Arrouasse, Caroline Boucle, Salwa Abid, Emilie Sbidian, Christina Bergqvist, Pierre Wolkenstein, Véronique Godot, Jean-François Deleuze, Yves Lévy, Piotr Topilko, Etienne Audureau, Sophie Hue
Original Article November 2025 -
From Reactive to Predictive: Advancing Biologic Dosing in DermatologyAnke Eylenbosch, Ruoheng Wei, Rani Soenen, Catherine Smith, Joseph F. Standing, Satveer Mahil, Jo Lambert
Review Article November 2025 -
Ultra-high frequency ultrasound predicts baricitinib response in alopecia areata: Towards personalized treatmentFlavia Manzo Margiotta, Alessandra Michelucci, Bianca Cei, Giorgia Salvia, Giammarco Granieri, Alessandra Biagi, Riccardo Morganti, Marco Romanelli, Valentina Dini
Letter to the Editor October 2025 -
Targeted Management of Vascular AnomaliesJessie T. Lu, Marra Aghajani, Deshan F. Sebaratnam
Review Article October 2025 -
Personalized biologic treatments for patients with Darier disease result in varying responsesMonika Ettinger, Teresa Burner, Angelika Lackner, Isabella Deli, Judith Traxler, Sabine Altrichter, Iris K. Gratz, Susanne Kimeswenger, Emmanuella Guenova, Wolfram Hoetzenecker
Letter to the Editor September 2025 -
Eczematous reaction to guselkumab successfully treated with upadacitinibHector Moreno-Davila, Pablo Gamez-Siller, Rodolfo Franco-Marquez, Jose Antonio Garcia-Muñiz, Dionicio Angel Galarza-Delgado, Jesus Alberto Cardenas-de la Garza
Letter to the Editor July 2025